HEPA Filter Manufacturer in India: Complete Guide for Pharma, Hospitals & Cleanrooms
High-Efficiency Particulate Air (HEPA) filters are the heart of every cleanroom. Whether it’s a pharmaceutical sterile facility, a biotech research lab, a hospital ICU, or electronic chip manufacturing, HEPA filters ensure the highest level of air purity.
As the demand for contamination control grows across India, choosing the right HEPA filter manufacturer in India becomes crucial. The quality of your HEPA filters directly affects:
- product quality
- compliance (GMP/ISO/FDA)
- microbial control
- cleanroom stability
- operational safety
This blog explains everything you need to know about HEPA filters — types, grades, construction, applications, and selection parameters.
1. What Is a HEPA Filter?
A HEPA (High-Efficiency Particulate Air) filter removes ultrafine airborne particles, including:
- viruses
- bacteria
- mold spores
- aerosols
- dust
- micro-particles as small as 0.3 microns
Efficiency Grades (EN1822 Standard)
- H13: 99.95%
- H14: 99.995%
- U15: 99.9995% (rarely used except biosafety labs)
Most Indian cleanrooms use H13 and H14 HEPA filters.
2. Types of HEPA Filters in India
Different industries require different HEPA construction styles. Below are the most commonly used types:
A. Mini Pleat HEPA Filters
The preferred modern HEPA filter type.
Features:
- compact design
- increased surface area
- low pressure drop
- higher airflow
- long service life
Ideal For:
- pharmaceutical manufacturing
- labs & IVF centers
- modular cleanrooms
- hospitals
Mini pleat HEPA filters are widely used due to energy efficiency and ease of installation.
B. Deep Pleat HEPA Filters
The traditional HEPA design.
Features:
- aluminum or GI separators
- thicker construction
- withstands high airflow
- extremely durable
Ideal For:
- large HVAC systems
- AHUs in manufacturing plants
- high-volume cleanrooms
Deep pleat filters are still popular for heavy-duty ventilation requirements.
C. Gel-Seal HEPA Filters
Gel-seal technology ensures zero leakage, which is mandatory for sensitive sterile environments.
Features:
- gasket-free sealing
- 100% leak-proof barrier
- ideal for terminal boxes
Used In:
- biosafety labs
- hospital OTs
- sterile pharma rooms
- oncology labs
- BSL2/BSL3 facilities
D. High Temperature HEPA Filters
Designed to work in 200–250°C temperatures.
Used In:
- dry heat sterilizers
- ovens
- depyrogenation tunnels
- R&D facilities
These filters require special glass fiber media and metallic frames.
3. How HEPA Filters Are Made Construction Explained
A high-quality HEPA filter must follow strict standards — this is what a trusted HEPA filter manufacturer in India provides.
Components:
- Filter Media: micro-glass fiber paper
- Frame: Aluminum, GI, SS304
- Separator: mini pleat hot-melt / aluminum separators
- Sealant: polyurethane or epoxy
- Gasket: neoprene, EVA, or gel
A reliable HEPA ensures:
- durability
- chemical resistance
- low pressure drop
- high mechanical strength
4. HEPA Filters in Clean Rooms
HEPA filters are installed at the final filtration stage to achieve controlled particle levels.
Cleanroom Classes & Required HEPA:
| Cleanroom Class | HEPA Grade |
| ISO 5 | H14 |
| ISO 6 | H13/H14 |
| ISO 7 | H13 |
| ISO 8 | H13 |
Where HEPA Filters Are Installed? Check out below
- Terminal HEPA boxes
- AHUs
- Fan Filter Units (FFUs)
- Laminar Airflow Units
- BSCs (Biosafety Cabinets)
- OT Laminar Flow Ceilings
5. Which type of HEPA Filters in AHU & HVAC Systems?
In HVAC-based cleanrooms:
- Pre filters – remove large particles
- Fine filters – trap medium particles
- HEPA filters – remove 0.3 micron contaminants
HEPA is the final stage filter before air enters the cleanroom.
Key requirements:
- low resistance
- leak-proof design
- high airflow compatibility
- proper sealing
- compliance with EN1822
6. What are the HEPA Filter Applications in India?
Pharmaceutical Industry
- sterile manufacturing
- API facilities
- vaccine production
- tablet compression rooms
Hospitals & Healthcare
- OT LAF ceilings
- ICU & NICU
- isolation rooms
Biotechnology
- molecular labs
- cell culture rooms
Microelectronics
- semiconductor production
Food & Beverages
- aseptic filling lines
R&D Labs
- biosafety cabinets
- laminar flow units
7. How to Choose the Right HEPA Filter?
A. Choose Correct HEPA Grade
- H13 for general cleanrooms
- H14 for sterile rooms
- U15 for biosafety
B. Check Pressure Drop
Lower resistance = lower electricity cost.
C. Choose Correct Size
Frame dimensions must fit AHU/terminal box.
D. Pick the Right Construction Type
Mini pleat – energy efficient
Gel-seal – sterile environments
Deep pleat – high airflow
E. Verify Standards
Choose HEPA filters with:
- EN 1822 test report
- DOP/PAO test certificate
- manufacturing batch certification
8. Signs Your HEPA Filter Needs Replacement
Replace when:
- pressure drop increases beyond limit
- airflow becomes unstable
- contamination counts rise
- physical damage occurs
- filter reaches 2–3 years (standard lifecycle)
9. Benefits of Using High-Quality HEPA Filters
- stronger contamination control
- reduced cleanroom failures
- extended equipment lifespan
- improved HVAC efficiency
- lower energy cost
- long-term operational safety
A reputable HEPA filter manufacturer in India offers filters that meet global standards and withstand India’s environmental conditions.
Conclusion
HEPA filters are the core of any controlled cleanroom environment. Whether you operate a pharmaceutical plant, hospital OT, research laboratory, or manufacturing facility, choosing the right HEPA grade, construction type, and certified manufacturer is essential.
Look for mini pleat or gel-seal HEPA filters that comply with EN1822 testing, provide low pressure drop, and ensure consistent efficiency.
If you need high-quality Clean Room Filters or HEPA filters in India, always prioritize performance, certification, airflow compatibility, and longevity.
FAQs
A good HEPA filter manufacturer should provide:
– Tested filters as per EN 1822 (H13, H14, U15 grades)
– DOP/PAO test certificates and batch-wise test reports
– Options in mini pleat, deep pleat, gel-seal, and high-temperature HEPA
– Proper technical support for size selection, pressure drop, and airflow
– Clear guidance for pharma, hospital, biotech, or electronics applications
It depends on your cleanroom class and process:
– H13 – General cleanrooms, ISO 7–8, many HVAC-based cleanrooms
– H13 / H14 – ISO 6, critical but not ultra-sterile areas
– H14 – Sterile pharma rooms, OTs, ICU/NICU, ISO 5 areas
– U15 – Only for very high-risk biosafety labs (BSL2/BSL3) and special R&D
Your HVAC consultant or HEPA filter manufacturer can match HEPA grade to ISO class for you.
Replacement frequency depends on usage and contamination level, but commonly:
– Every 2–3 years in normal conditions (standard lifecycle)
– Earlier if pressure drop goes above the recommended limit
– If particle or microbial counts increase during validation
– Immediately if there is physical damage, leakage, or gasket failure
Regular DOP/PAO testing and pressure monitoring will tell you when replacement is due.
For compliance and audits (GMP, ISO, FDA), you should ask for:
– EN 1822 test report for H13/H14/U15 grade
– DOP/PAO integrity test certificate
– Manufacturing batch certificate with efficiency and pressure drop values
– Material specs for media, frame, sealant, and gasket
– Validation support for ISO 14644 and GMP WHO cleanrooms
These documents make regulatory inspections much easier.
Common warning signs include:
– Sudden rise in pressure drop across the HEPA filter
– Unstable airflow at terminal HEPA boxes or laminar flow units
– Failed particle or microbiological counts during routine testing
– Visible damage, corrosion, or gasket/gel leakage
– More frequent cleanroom classification failures
If any of these show up, the filter should be tested immediately and replaced if required.